Journal of Oral and Maxillofacial Pathology

CASE REPORT
Year
: 2011  |  Volume : 15  |  Issue : 1  |  Page : 39--45

Oral lesions associated with nevirapine-related Stevens Johnson syndrome: A report of four cases


S Balasundaram1, K Ranganathan2, K Umadevi2, R Gunaseelan3, N Kumaraswamy4, Sunithi Solomon4, Bella Devaleenol4, Pradeep Ambrose4 
1 Department of Oral Pathology, Chennai Dental Research Foundation, Chennai, Tamil Nadu, India
2 Department of Oral Pathology, Ragas Dental College and Hospitals, Chennai, India
3 Department of Oral Pathology, Chennai Dental Research Foundation, Chennai, India
4 Department of Oral Pathology, YRG Care, Chennai, India

Correspondence Address:
S Balasundaram
Department of Oral and Maxillofacial Pathology, Chennai Dental Research Foundation, No 56, Dr. Radhakrishnan Salai, Mylapore, Chennai - 600 004, Tamil nadu
India

Nevirapine is a non-nucleoside reverse transcriptase inhibitor, widely used in combination with other antiretroviral agents for treatment of HIV infection. Steven Johnson syndrome (SJS) is the major toxicity of nevirapine. We describe here four cases of SJS in HIV seropositive patients following nevirapine therapy. In all four cases cutaneous hypersensitivity reaction was seen with extreme oral lesions, three patients presented clinically with elevated liver enzymes and hepatitis, and two patients had ocular involvement.


How to cite this article:
Balasundaram S, Ranganathan K, Umadevi K, Gunaseelan R, Kumaraswamy N, Solomon S, Devaleenol B, Ambrose P. Oral lesions associated with nevirapine-related Stevens Johnson syndrome: A report of four cases.J Oral Maxillofac Pathol 2011;15:39-45


How to cite this URL:
Balasundaram S, Ranganathan K, Umadevi K, Gunaseelan R, Kumaraswamy N, Solomon S, Devaleenol B, Ambrose P. Oral lesions associated with nevirapine-related Stevens Johnson syndrome: A report of four cases. J Oral Maxillofac Pathol [serial online] 2011 [cited 2020 Oct 24 ];15:39-45
Available from: https://www.jomfp.in/article.asp?issn=0973-029X;year=2011;volume=15;issue=1;spage=39;epage=45;aulast=Balasundaram;type=0