Journal of Oral and Maxillofacial Pathology

ORIGINAL RESEARCH
Year
: 2003  |  Volume : 7  |  Issue : 2  |  Page : 44--45

Estimation of serum antioxidant enzymes superoxide dismutase and glutathione peroxidase in oral submucous fibrosis: A biochemical study


AK Uikey1, VK Hazarey1, SM Vaidhya2 
1 Department of Oral and Maxillo Facial Pathology and Microbiology, GDCH, Nagpur, India
2 Professor of Biochemistry, Government Medical College and Hospital, Mumbai, India

Correspondence Address:
V K Hazarey
Department of OMFPM, GDCH, Nagpur 63
India

The aim of the present study was to estimate the serum status of antioxidants, superoxide dismutase (SOD) and glutathione peroxidase (GPX) in oral submucous fibrosis (OSF) which is a precancerous condition common in Indian subcontinent. A total of sixty subjects were included in the study comprising of 30 cases of oral submucous fibrosis and 30 healthy controls. The haemolysate levels of antioxidant enzymes (SOD and GPX) were estimated using Ciba corning express plus autoanalyzer for spectrometry. In OSF, serum antioxidant enzyme levels were found to be decreased (mean SOD 86.6320.36 and mean GPX 1.500.30 U/ml) compared to the control group (mean SOD 127.118.14 and mean GPX 2.710.43 U/ml). The results suggest that low values of SOD and GPX may be associated with the development of carcinoma in oral submucous fibrosis.


How to cite this article:
Uikey A K, Hazarey V K, Vaidhya S M. Estimation of serum antioxidant enzymes superoxide dismutase and glutathione peroxidase in oral submucous fibrosis: A biochemical study.J Oral Maxillofac Pathol 2003;7:44-45


How to cite this URL:
Uikey A K, Hazarey V K, Vaidhya S M. Estimation of serum antioxidant enzymes superoxide dismutase and glutathione peroxidase in oral submucous fibrosis: A biochemical study. J Oral Maxillofac Pathol [serial online] 2003 [cited 2021 Jun 19 ];7:44-45
Available from: https://www.jomfp.in/article.asp?issn=0973-029X;year=2003;volume=7;issue=2;spage=44;epage=45;aulast=Uikey;type=0