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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists

Year : 2021  |  Volume : 25  |  Issue : 1  |  Page : 204
Noncalcifying clear-cell variant of calcifying epithelial odontogenic tumor: A case report and review

Department of Oral and Maxillofacial Pathology and Microbiology, YMT'S Dental College and PG Institute, Navi Mumbai, Maharashtra, India

Correspondence Address:
Sheetal Choudhari
Department of Oral and Maxillofacial Pathology and Microbiology, YMT'S Dental College and PG Institute, Kharghar, Navi Mumbai - 410 210, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jomfp.JOMFP_212_20

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Clear-cell tumors of the head and neck are biologically diverse consisting of benign, malignant and metastatic lesions. These tumors pose a diagnostic challenge. In the oral cavity, these may be derived from odontogenic/nonodontogenic epithelium or from mesenchyme or can be metastatic. Odontogenic tumors with clear-cell change are rare. Calcifying epithelial odontogenic tumor (CEOT) is a rare, benign, locally aggressive odontogenic epithelial tumor affecting the jaw. Here, we report a case of clear-cell variant of CEOT with its histopathological differential diagnosis. A 43-year-old male patient with swelling in his lower right back tooth region showed a well-defined radiolucent lesion with smooth corticated periphery on radiograph. On incisional biopsy, tumor showed small sheets, cords and islands of odontogenic epithelium with nests of clear cells with no evidence of calcification. A final diagnosis of CEOT was established by differentiating other odontogenic and nonodontogenic lesions on the basis of clinical, radiographic, histopathologic and special stain features.

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Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
Online since 15th Aug, 2007