Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contact Us Login 
An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
ORIGINAL ARTICLE Table of Contents   
Year : 2020  |  Volume : 24  |  Issue : 3  |  Page : 517-522
Evaluation of antifungal activity of mint, pomegranate and coriander on fluconazole-resistant Candida glabrata


Department of Oral and Maxillofacial Pathology and Microbiology, SRM Dental College, Chennai, Tamil Nadu, India

Correspondence Address:
Lekshmy Jayan
Department of Oral and Maxillofacial Pathology and Microbiology, SRM Dental College, Ramapuram, Chennai, Tamil Nadu
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jomfp.JOMFP_355_19

Rights and Permissions

Introduction: Antifungal resistance shown by different species of Candida has affected the management of candidiasis drastically. This has led to the need for newer safer therapeutic alternatives for their management. Phytochemical agents have been long known to possess numerous medicinal activities. Aim: The aim of this study was to evaluate the efficacy and resistance of fluconazole and to compare the antifungal effects of Coriandrum sativum, Mentha piperita and Punica granatum in Candida glabrata. Materials and Methods: The organism was inoculated into a specific medium, and extracts are added at serial dilutions and incubated to evaluate the zone of inhibition. Results: All the three extracts showed statistically significant and superior antifungal activity to fluconazole in fluconazole-resistant C. glabrata. Conclusion: Although the extracts showed superior antifungal activity in resistant C. glabrata strains, further studies are needed to evaluate these extracts in patients to see if their efficacy is impeded by any systemic or local factors in the body.


[FULL TEXT] [PDF]*
Print this article  Email this article
    

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed306    
    Printed28    
    Emailed0    
    PDF Downloaded37    
    Comments [Add]    

Recommend this journal

 

Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
Online since 15th Aug, 2007