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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists

CASE REPORT Table of Contents   
Year : 2013  |  Volume : 17  |  Issue : 1  |  Page : 149
Leimyosarcoma of the buccal mucosa and review of literature

1 Department of Oral and Maxillofacial Pathology, Sinhgad Dental College and Hospital, Maharashtra, India
2 Department of Oral and Maxillofacial Pathology, M. A. Rangoonwala College of Dental Sciences and Research Centre, Pune, Maharashtra, India

Correspondence Address:
Deepak Kumar J Nagpal
Department of Oral and Maxillofacial Pathology, Sinhgad Dental College and Hospital, Pune 411 041, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-029X.110732

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Leiomyosarcoma (LMS) is an uncommon malignant spindle cell tumor of the head and neck region. The occurrence is particularly rare in the buccal mucosa of the oral cavity. It is a rapidly growing tumor with aggressive behavior and poor prognosis. Method: This article presents a rare case of primary leimyosarcoma of the buccal mucosa in a 35 year old female and retrospective analysis of primary oral LMS published in the English literature since past 20 years is done. Diagnosis was confirmed by immunohistochemistry profile showing positivity for vimentin, smooth muscle actin (SMA), high proliferative index displayed by Ki-67, focal positivity for pan-CK and negativity for S-100. Conclusion: Based on the presence of malignant spindle cells showing positivity for vimentin and SMA, a diagnosis of leiomyosarcoma was made.

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Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
Online since 15th Aug, 2007