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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists

CASE REPORT Table of Contents   
Year : 2013  |  Volume : 17  |  Issue : 1  |  Page : 106-109
Multisystem Langerhans cell histiocytosis presenting as an oral lesion

1 Department of Oral Pathology, Oral Medicine and Periodontology, University of Malaya, Kuala Lumpur, Malaysia
2 Department of Faculty of Dentistry, Primary Dental Care Unit, University of Malaya, Kuala Lumpur, Malaysia
3 Department of Oral Cancer Research and Coordinating Center, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia
4 Department of Pediatric Dentistry, Hospital Sultanah Aminah, Johor Bahru, Malaysia

Correspondence Address:
Kallarakkal Thomas George
Department of Oral Pathology, Oral Medicine and Periodontology, Faculty of Dentistry, University of Malaya, 50603, Kuala Lumpur
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-029X.110694

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Langerhans cell histiocytosis (LCH) is a rare proliferative disorder in which the pathologic Langerhans cells infiltrate and destroy the tissues. Patients with LCH present varied clinical manifestations. Cutaneous lesions in LCH manifest as vesiculopapular eruptions that often mimic various infectious diseases particularly in infants. We present a case of a female infant with an ulcerative lesion intraorally. The baby was asymptomatic otherwise. A detailed history revealed the presence of cutaneous lesions that was overlooked by her parents. Conclusion: This report tries to briefly discuss the current concepts regarding the etiology of LCH. An attempt has been made to emphasis the need for a through systemic examination. The protocol of investigative procedures to be adopted in LCH is also discussed.

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Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
Online since 15th Aug, 2007