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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists

KNOW THIS FIELD Table of Contents   
Year : 2009  |  Volume : 13  |  Issue : 2  |  Page : 61

Know this field

Department of Oral and Maxillofacial Pathology, Ragas Dental College and Hospital, Chennai, India

Date of Web Publication10-Nov-2009

Correspondence Address:
N Lavanya
Department of Oral and Maxillofacial Pathology, Ragas Dental College and Hospital, Chennai
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Source of Support: None, Conflict of Interest: None

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How to cite this article:
Lavanya N, Joshua E, Umadevi K M, Ranganathan K. Know this field. J Oral Maxillofac Pathol 2009;13:61

How to cite this URL:
Lavanya N, Joshua E, Umadevi K M, Ranganathan K. Know this field. J Oral Maxillofac Pathol [serial online] 2009 [cited 2021 Aug 1];13:61. Available from: https://www.jomfp.in/text.asp?2009/13/2/61/57670

   Case Details Top

  • 35 year old female
  • Pain and swelling in left lower face past twenty days.
  • H/o swelling after extraction of left lower back tooth one month back
  • Swelling subsides on taking antibiotics and re-occurs
  • Swelling is warm, very tender, diffuse, cystic in nature, soft in consistency over the left angle of mandible
  • Intra orally 38 missing. A localised swelling, tender in retromolar region behind 38
  • Provisional diagnosis:
  • Submassetric space infection
  • Excisional biopsy
Site - Intraorally left retromolar region

   Histopathology Top

Nodule of fibrovascular connective tissue exhibiting

  • Necrotic areas, Foci of mixed inflammatory cell infiltrate, nerve bundles [Figure 1] adipose tissue and clusters of squamous like epithelial cells areas depicted in the adjacent six photomicrographs.
  • All these cliusters of squamous like epithelial cells interspersed with clear cells were adjacent to bundles of nerve tissue [Figure 2],[Figure 3],[Figure 4],[Figure 5],[Figure 6]

   Differential Diagnosis Top

01) Malignant squamous epithelial islands - Squamous cell carcinoma 2) Mucoepidermoid carcinoma 3) Adenocarcinoma 4) Metastatic deposits 5) Perineural invasion by carcinoma 6. Odontogenic tumours (Squamous Odontogenic Tumour, Adenomatoid odontogenic tumour, Ameloblastoma) 7) Normal findings like Odontogenic rests in the tissue or Organ of Chevitz.

   Diagnosis Top

Chronic granulation tissue (associated with space infection) with Juxta Oral Organ Of Chevitz in the tissue

   Juxta Oral Organ of Chevitz Top

These are a cluster of squamous epithelial cells, some times interspersed with clear cells and duct like appearance found microscopially in the tissue taken from the site where inferior alveolar nerve block is given i.e. medial to mandibular internal oblique ridge and pterygomandibular raphe. These are closely associated with myelinated nerve bundles and are suggested to be neuroepithelial structures with a neuroendocrine function.

   Points to Remember Top

  • Site of biopsy.
  • Characteristic histopathological appearance, PAS positive intact basement membrane
  • Clinical presentation of the lesion.

   References Top

  • Juxtaoral Organ(Chevitz Organ): Morphology and Clinical aspects. Baltimore, Urban and Schwarzberg, 1982 (Monograph)
  • The juxtaoral organ of Chievitz . Int J Surg Pathol. 2003 Jan; 11(1):37.


  [Figure 1], [Figure 2], [Figure 3], [Figure 4], [Figure 5], [Figure 6]


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