Journal of Oral and Maxillofacial Pathology

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Year
: 2012  |  Volume : 16  |  Issue : 1  |  Page : 156--158

Ameloblastic carcinoma: Sometimes a challenge


Samapika Routray, Sumit Majumdar 
 Department of Oral Pathology and Microbiology, Gitam Dental College and Hospital, Gandhinagar Campus, Rushikonda, Vishakapatanam, India

Correspondence Address:
Samapika Routray
Department of Oral Pathology and Microbiology, Gitam Dental College and Hospital, Gandhinagar Campus, Rushikonda, Vishakapatanam
India




How to cite this article:
Routray S, Majumdar S. Ameloblastic carcinoma: Sometimes a challenge.J Oral Maxillofac Pathol 2012;16:156-158


How to cite this URL:
Routray S, Majumdar S. Ameloblastic carcinoma: Sometimes a challenge. J Oral Maxillofac Pathol [serial online] 2012 [cited 2019 Oct 22 ];16:156-158
Available from: http://www.jomfp.in/text.asp?2012/16/1/156/92998


Full Text

A 60-year-old male reported with pain and extraoral swelling in the left lower third of the face. Clinically, a 2 cm × 2 cm bony hard swelling was seen extending up to the left angle of the mandible. The swelling was tender on palpation, with no signs of parasthesia. Intraorally, the ulcer was 1 cm × 3 cm in size and showed white slough and and an indurated border. Radiographically, a diffuse radiolucency was seen.

 Histopathology





Ulcerated mucosal surface with acute inflammation is seen, along with pleomorphic epithelial cells irregularly arranged in cords and nests [Figure 1] and [Figure 2]. {Figure 1}{Figure 2}Moderate acute inflammation with keratotic debris is seen in the islands lined by tall columnar cells showing nuclear atypia and mitotic activity [Figure 3],[Figure 4],[Figure 5],[Figure 6] and [Figure 7]. {Figure 3}{Figure 4}{Figure 5}{Figure 6}{Figure 7}Intervening stroma is vascular and shows dense lymphocytic infiltration. The islands of tall columnar cells show a high degree of pleomormhism and mitotic activity; the intervening stroma is vascular [Figure 8],[Figure 9],[Figure 10],[Figure 11],[Figure 12] and [Figure 13].{Figure 8}{Figure 9}{Figure 10}{Figure 11}{Figure 12}{Figure 13}

 Differential Diagnosis



Conventional ameloblastoma does not show the same intensity of pleomorphism, whereas squamous differentiation in ameloblastoma resembling keratotic debris might be confused with squamous cell carcinoma.

 Final Diagnosis



The histopathological features are suggestive of ameloblastic carcinoma.