Journal of Oral and Maxillofacial Pathology

KNOW THIS FIELD
Year
: 2005  |  Volume : 9  |  Issue : 1  |  Page : 20-

Know this field


B Sivapathasundharam, S Lavanya, G Sivakumar 
 Department or Oral and Maxillo Facial Pathology, Meenakshi Ammal Dental College and Hospital, Chennai, India

Correspondence Address:
B Sivapathasundharam
Department or Oral and Maxillo Facial Pathology, Meenakshi Ammal Dental College and Hospital, Chennai
India




How to cite this article:
Sivapathasundharam B, Lavanya S, Sivakumar G. Know this field.J Oral Maxillofac Pathol 2005;9:20-20


How to cite this URL:
Sivapathasundharam B, Lavanya S, Sivakumar G. Know this field. J Oral Maxillofac Pathol [serial online] 2005 [cited 2020 Feb 27 ];9:20-20
Available from: http://www.jomfp.in/text.asp?2005/9/1/20/39054


Full Text

 Case Details



A 39-year-old female reported with the chief complaint of mobile lower front teeth since 6 months and was associated with tingling sensation over the gums. Past history of loss of lower front teeth since 5 years, associated with swelling and pus discharge. Extra orally, single palpable, mobile, and tender right submandibular lymph node seen. 41,42,43, and 44 were missing. 31 and 45 were mobile. 31, 32 and 45 were migrated..

OPG showed unilocular radiolucency extending from 45 to 31 region, involving the roots of 45 and 31 with scalloped borders. The root of 31 was resorbed.

 Microscopic Findings



Spindle shaped cells with wavy and tapered nuclei were seen arranged in fascicles in an haphazard manner. Few chronic inflammatory cells were seen.

 Special Stains



Toluidine blue: Purplish mast cells seen

S-100 protein: Focal areas of positivity.

 Discussion



Histopathology was suggestive of intraosseous neurofibroma with the differential diagnosis including schwannoma, myxoma, desmoplastic fibroma, and fibrous histiocytoma.

Lack of encapsulation and focal areas of positivity for SI00 protein ruled out schwannoma, as the latter shows encapsulation and diffuse positivity for S-100. Positivity for S-100 protein ruled out myxoma, desmoplastic fibroma, and fibrous histiocytoma.

Presence of mast cells strongly supported neurofibroma.

 Final Diagnosis



Solitary intra-osseous neurofibroma of mandible