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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
CASE REPORT - MISCELLANEOUS Table of Contents   
Year : 2020  |  Volume : 24  |  Issue : 4  |  Page : 135-138
Immunoglobulin G4-related chronic sclerosing sialadenitis: An emerging entity


Department of Pathology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India

Correspondence Address:
Charusheela Rajesh Gore
Prof. and Head, Department of Pathology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pimpr, Pune - 411 018, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jomfp.JOMFP_83_17

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Chronic sclerosing sialadenitis is associated with the immunoglobulin G4 (IgG4)-related disease (RD) spectrum. IgG4-RD is a newly recognized immunomediated fibroinflammatory condition characterized by several features: a tendency to form tumefactive lesions at multiple sites, lymphoplasmacytic infiltrate, fibrosis and obliterative phlebitis. Often but not always, the serum IgG4 concentrations are also elevated. Immunohistochemistry for IgG4 is helpful to clinch the diagnosis. Here, we describe a case of 65-year-old male with IgG4-related chronic sclerosing sialadenitis of the s ubmandibular gland. We have discussed the histopathological criteria to diagnose this entity.


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Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
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