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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
CASE REPORT - LYMPHOPROLIFERATIVE DISORDERS Table of Contents   
Year : 2019  |  Volume : 23  |  Issue : 4  |  Page : 7-11
Evaluation of a case of diffuse large B-cell lymphoma


Department of Oral and Maxillofacial Pathology and Microbiology, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, Punjab, India

Correspondence Address:
Ramandeep Singh Narang
Department of Oral and Maxillofacial Pathology and Microbiology, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, Punjab
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jomfp.JOMFP_100_17

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Lymphomas are a group of malignant blood cell tumors that develop from lymphocytes representing 2.2% of all malignant neoplasms of the head and neck. Two main categories of lymphomas are Hodgkin's lymphoma and non-Hodgkin's lymphoma (NHL) of which 90% are of the NHL type. Several classification systems have existed for lymphomas, the objectives of which are to help in identification of homogeneous group of well-defined entities and facilitating the recognition of uncommon diseases that require further classification as it affects prognosis and therapeutic implications. Diffuse large B-cell lymphoma (DLBCL) is the most common NHL in the oral cavity involving Waldeyer's ring, base of the tongue, buccal mucosa and hard palate. DLBCL can be divided into germinal center B-cell-like, activated B-cell-like or type 3 gene expression profiles. This paper highlights a case report of DLBCL revisiting the intricacies and difficulties involved in establishing a diagnosis.


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Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
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