Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contact Us Login 
An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
ORIGINAL ARTICLE Table of Contents   
Year : 2019  |  Volume : 23  |  Issue : 3  |  Page : 356-362
Histomorphological comparison of pleomorphic adenoma in major and minor salivary glands of oral cavity: A comparative study


1 Department of Oral and Maxillofacial Pathology, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Bengaluru, Karnataka, India
2 Department of Prosthodontics, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Bengaluru, Karnataka, India
3 Department of Oral Medicine and Radiology, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Bengaluru, Karnataka, India

Correspondence Address:
S Nonitha
Department of Oral Medicine and Radiology, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, Bengaluru - 560 032, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jomfp.JOMFP_91_19

Rights and Permissions

Background and Objectives: Pleomorphic adenoma, being the most common benign tumors of salivary gland, is morphologically characterized by a biphasic pattern containing the epithelial and mesenchymal components. The modified myoepithelial cells present are thought to play an important role in its histologic diversity by the formation of extracellular matrix. The aim of the present study was to observe, compare and correlate the histomorphological diversity of epithelial and stromal components along with different morphological cell types of modified myoepithelial cells. Materials and Method: Histomorphological features were compared in twenty cases of pleomorphic adenoma of major salivary glands and twenty cases of minor salivary glands using hematoxylin and eosin stains. The features were analyzed by observing under the light microscope. Results: Statistical analysis showed significance of plasmacytoid cells, and squamous metaplasia was extensive with formation of keratin cyst-like structure resembling cystic pleomorphic adenoma, in minor salivary gland tumors. Conclusion: Plasmacytoid cells, squamous cells and areas of hyalinization were observed predominantly in major salivary gland tumors compared to minor salivary glands. Keratin pearls were predominant in minor salivary gland tumors.


[FULL TEXT] [PDF]*
Print this article  Email this article
    

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed405    
    Printed3    
    Emailed0    
    PDF Downloaded54    
    Comments [Add]    

Recommend this journal

 

Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
Online since 15th Aug, 2007