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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
CASE REPORT Table of Contents   
Year : 2018  |  Volume : 22  |  Issue : 4  |  Page : 16-19
A curious case of central odontogenic fibroma: A novel perspective


1 Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India
2 Department of Oral Pathology and Microbiology, Kusum Devi Sunderlal Dugar Jain Dental College, Kolkata, West Bengal, India
3 Consultant, Craniofacial Services, Hannah Joseph Institute of Neurosciences, Madurai, Tamil Nadu, India

Correspondence Address:
Dr. Raghu Radhakrishnan
Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal - 576 104, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jomfp.JOMFP_156_16

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We appraise a case of central odontogenic fibroma (COF) with unusual histologic features of entrapped neural elements and mast cells. The presence of mast cells attributed to the release of stem cell factor, the principal growth and activating factor of mast cells. A putative role for C-kit and mast cells in the pathogenesis of COF is described.


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Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
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