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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
CASE REPORT Table of Contents   
Year : 2017  |  Volume : 21  |  Issue : 3  |  Page : 429-433
Giant-cell fibroma: Understanding the nature of the melanin-laden cells


1 Department of Oral Pathology, Manipal College of Dental Sciences, Manipal, Karnataka, India
2 Department of General pathology, Manipal College of Dental Sciences, Manipal, Karnataka, India

Correspondence Address:
Dr. Raghu Radhakrishnan
Department of Oral Pathology, Manipal College of Dental Sciences, Manipal - 576 104, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jomfp.JOMFP_209_16

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Giant-cell fibroma is a localized, benign fibrous mucosal mass, which clinically mimics any other fibroepithelial growth, and its distinction from other lesions is on the basis of its peculiar histopathology. A case of giant-cell fibroma with stroma strewn with brown pigment-laden cells is presented herewith. Immunohistochemical staining aided with histochemical reaction to understand the origin of these cells was carried out. Various mechanisms that explain the presence of melanin granules in reactive lesions of giant-cell fibroma is discussed in the present report.


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