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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
CASE REPORT Table of Contents   
Year : 2017  |  Volume : 21  |  Issue : 3  |  Page : 425-428
Clear-cell variant of squamous cell carcinoma in maxilla as primary lesion: A rare case


1 Department of Oral Pathology, Pt. B. D. Sharma University of Health Sciences, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India
2 Department of Oral Surgery, Pt. B. D. Sharma University of Health Sciences, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India
3 Department of General Pathology, Pt. B. D. Sharma University of Health Sciences, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India

Correspondence Address:
Dr. Anju Devi
Department of Oral Pathology, Post Graduate Institute of Dental Sciences, Rohtak, Haryana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jomfp.JOMFP_180_16

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Oral squamous cell carcinoma with prominent clear-cell differentiation is a rare occurrence with incompletely understood etiology. We report a case of a 55-year-old male working in a steel factory presented with an ulcerated swelling on maxillary alveolar ridge, a rare site. Histopathology showed sheets of squamous cells with clear cell differentiation and features of malignancy. Periodic acid–Schiff and mucicarmine stains showed negative reaction. Immunohistochemical study using antibody for cytokeratin and epithelial membrane antigen revealed diffuse and intense positivity. The neoplastic cells showed complete negative reaction with antibodies for S-100 and vimentin.


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Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
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