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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
CASE REPORT Table of Contents   
Year : 2014  |  Volume : 18  |  Issue : 3  |  Page : 460-463
Fatal rhino-orbito-cerebral mucormycosis in a healthy individual


1 Department of Oral Pathology and Microbiology, Panineeya Institute of Dental Sciences and Research Center, Kamala Nagar, Dilsukhnagar, Hyderabad, India
2 Department of Pathology, Osmania Medical College, Koti, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Rama Krishna Angali
Senior lecturer, Department of Oral Pathology and Microbiology, Panineeya Institute of Dental Sciences and Research Center, Road No: 5, Kamalanagar, Dilsukhnagar, Hyderabad - 500 060
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-029X.151355

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Rhino-orbital-cerebral zygomycosis is a potentially lethal, opportunistic, fungal infection with protean manifestations, rapid progression, unpredictable course and high mortality. It is associated with angioinvasion and infarction, usually observed in diabetic ketoacidosis, immuno-compromised states and rarely reported in an apparently normal host. We present a case of an18-year-old patient with a chronic, painful, non healing ulcer with necrotic margins over the right side of the face which extended to both orbits involving eyes within a period of 1.5 month. Later he developed severe headache, decreased vision, inability to speak, seizures and status epilepticus with fatal outcome. Awareness of its occurrence in normal patients with prompt diagnosis and appropriate management may improve the outcome and decrease mortality.


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