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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
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CASE REPORT  
Year : 2014  |  Volume : 18  |  Issue : 1  |  Page : 149
 

Lipoma of the submandibular space


Department of Ear, Nose and Throat, Sri Siddhartha Medical College, Agalakote, Tumkur, Karnataka, India

Date of Web Publication6-May-2014

Correspondence Address:
D C Sathyaki
Department of Ear, Nose and Throat, Sri Siddhartha Medical College, Agalakote, B. H. Road, Tumkur 572 107, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-029X.131948

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   Abstract 

Lipomas in the submandibular space are uncommon. This report describes a case of lipoma in the submandibular space. The clinical features, imaging study, histopathological features and management of the tumor are described.


Keywords: Adipocytes, lipoma, submandibular space


How to cite this article:
Sathyaki D C, Swarup R J, Mohan M, Varghese R. Lipoma of the submandibular space. J Oral Maxillofac Pathol 2014;18:149

How to cite this URL:
Sathyaki D C, Swarup R J, Mohan M, Varghese R. Lipoma of the submandibular space. J Oral Maxillofac Pathol [serial online] 2014 [cited 2020 Jul 4];18:149. Available from: http://www.jomfp.in/text.asp?2014/18/1/149/131948



   Introduction Top


Lipomas of the submandibular space are relatively uncommon. Prevalence is 1%. Conventionally, lipomas are divided into three types. Superficial lipomas (arise within subcutaneous tissue), deep lipoma (arise within deep soft tissue) and parosteal lipoma (arise within surfaces of the bone). [1] A total of 13% of lipomas are found in head and neck. Lipoma can harbor elements other than adipose tissue-like blood vessels, muscle fibers, fibroconnective tissue and bone tissue. [2] Although lipomas are generally diagnosed by clinical examination, imaging studies and histopathological examination can aid in establishing the diagnosis. Ultrasonography and histopathological examination aided us in establishing the diagnosis in the following case.


   Case report Top


An 55-year-old male patient presented with a swelling of the right submandibular region since 2 years. The swelling was painless and gradually progressive. Clinical examination revealed a smooth-surfaced, soft and non-tender mass (3 × 3 cm) with well-defined margins in the right submandibular region. The swelling was mobile, not fixed to the skin and the underlying bone. Clinically submandibular region swelling was suspected to be a lymph node or glandular enlargement [Figure 1].
Figure 1: Clinical picture showing a swelling in the right submandibular space with well defi ned margins

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Ultrasonography of the right submandibular region showed a well-circumscribed elliptical mass, which was relatively hyperechoic to the adjacent muscle that was adjacent to the base of the mandible. Fine-needle aspiration cytology showed fragments of adipose tissue consisting of cells with large vacuoles of fat and small peripherally located nuclei. Fragments also contained capillary vessels. It was negative for malignancy.

The patient underwent standard submandibular gland approach under local anesthesia with sedation. Excised mass showed a well-circumscribed lesion that was easily separated from the surrounding tissues [Figure 2]. Rest of the gland was normal. Marginal mandibular nerve was well preserved. Histopathological examination of the specimen showed adipocytes in lobules, separated by fibroconnective tissue and muscle bundles. These features were suggestive of lipoma [Figure 3].
Figure 2: Gross specimen being well encapsulated and separated from surrounding structures

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Figure 3: Photomicrograph showing adipocytes arranged in lobules. (H&E stain, 100)

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   Discussion Top


Although lipomas are relatively uncommon in the head and neck region, they should be considered as one of the differential diagnoses of neck masses. Annual incidence is 1 in 1000 individuals. Of those lipomas that occur in head and neck region, the most common location is posterior neck.

Lipomas, lipomatosis, angiolipomas, chondroidlipomas, lipoblastoma, lipoblostomatosis, spindle cell lipoma and pleomorphic lipomas are variants of this condition. The solitary lipoma is a common soft tissue tumor that results due to proliferation of histologically and chemically normal adipose tissue. Solitary lipoma is not developmental in origin and hence is not considered a hamartoma but rather a true neoplasm. Intraoperatively, lipomas may be seen as soft, yellow, shiny, smooth, mobile, encapsulated and occasionally lobulated subcutaneous masses. Microscopically, the lesions show lobular growth of mature adipocytes with demarcated borders, a fibrous capsule and a central vacuole. In some cases, lipomas can infiltrate into the adjacent muscles. Such lipomas are called infiltrative lipomas. They may be associated with syndromes such as hereditary multiple lipomatosis, Gardner's syndrome, Madelung's disease and Decrum's disease. [2]

There have been reports of deep intramuscular lipomas in the submandibular region by Adachi et al. [3] Pusiol et al., reported an oncocytic sialolipoma of submandibular gland. [1] Gultekin et al., reported a case of parosteal lipoma. [4] Furlong et al., in their study reported that lipomas in the head and neck are common in the parotid region followed by buccal mucosa and lip. [5]

When it comes to the diagnosis, sometimes clinical examination alone is not sufficient to identify the nature and exact location of the mass. In such a situation, imaging and histopathological examination can be useful. Ultrasound and magnetic resonance imaging can differentiate lipomas from other soft tissue tumors. In the case reported here, ultrasonography and histopathological examination were useful for the diagnosis. The prognosis of superficial lipoma is good and the risk of recurrence is low.

 
   References Top

1.Pusiol T, Franceschetti I, Scialpi M, Piscioli I. Oncocytic sialolipoma of the submandibular gland with sebaceous differentiation: A new pathological entity. Indian J Pathol Microbiol 2009;52:379-82.  Back to cited text no. 1
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2.Hemavathy S, Roy S, Kiresur A. Intraosseous angiolipoma of the mandible. J Oral Maxillofac Pathol 2012;16:283-7.  Back to cited text no. 2
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3.Adachi P, Kaba SP, Soubhia AM, Shinohara EH. Intermuscular lipoma of the submandibular space. Indian J Dent Res 2011;22:871-2.  Back to cited text no. 3
[PUBMED]  Medknow Journal  
4.Gultekin SE, Kahraman S, Karady K. Parosteal osteochondrolipoma of the mandible. J Oral Maxillofac Pathol 2012;16:280-2.  Back to cited text no. 4
    
5.Furlong MA, Fanburg-Smith JC, Childers EL. Lipoma of the oral and maxillofacial region: Site and subclassification of 125 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;98:441-50.  Back to cited text no. 5
    


    Figures

  [Figure 1], [Figure 2], [Figure 3]



 

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