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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
CASE REPORT Table of Contents   
Year : 2013  |  Volume : 17  |  Issue : 3  |  Page : 460-462
Bisphosphonate-induced osteoradionecrosis


1 Department of Oral Pathology and Microbiology, Institute of Dental Sciences and Hospital, Siksha O Anusandhan University, Bhubaneswar, Odisha, India
2 Department of Oral Medicine and Radiology, Institute of Dental Sciences and Hospital, Siksha O Anusandhan University, Bhubaneswar, Odisha, India
3 Departments of Pedodontia and Preventive Dentistry, Jagadguru Sri Shivarathreeshwara Dental College, Mysore, Karnataka, India

Correspondence Address:
Ruchi Bhuyan
Departments of Oral Pathology and Microbiology, Institute of Dental Sciences and Hospital, Siksha O Anusandhan University, Bhubaneswar - 751 015, Odisha
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-029X.125221

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Bisphosphonates (BPs) are a class of agents used to treat osteoporosis and malignant bone metastasis. Despite these benefits, osteonecrosis of the jaws has recently emerged as a significant complication in a subset of patients receiving these drugs. This case presentation focuses on a 62-year-old man with a 3-year history of monthly use of Zometa (zolendronic acid) for treatment of multiple myeloma, resulting in BP-related osteoradionecrosis of the jaws (BRONJ). This new entity remains a challenge with diagnosis as well as treatment. The goal of this paper is to improve clinicians understanding and provide a guideline for establishing a stage-specific diagnosis and prevention of BRONJ.


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Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
Online since 15th Aug, 2007