Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contact Us Login 
An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
CASE REPORT Table of Contents   
Year : 2011  |  Volume : 15  |  Issue : 3  |  Page : 311-315
Symmetric palatal swelling as the first clinical manifestation of a mantle cell non-Hodgkin's lymphoma: A case report and review of literature


1 Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, Martin-Luther-University, Halle-Wittenberg (S.), Germany
2 Institute of Pathology, Martin-Luther-University, Halle-Wittenberg (S.), Germany
3 Department of Neurosurgery, Martin Luther University, Halle Wittenberg (S.), Germany

Correspondence Address:
Konstanze Scheller
Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, Martin Luther University, Halle Wittenberg, Ernst Grube Strasse 40, 06120 Halle (S.)
Germany
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-029X.86703

Rights and Permissions

The mantle cell lymphoma (MCL) is a rare (3.7%) low-grade non-Hodgkin lymphoma originating from the B-cell precursor-subpopulation. The clinical appearance in the oral cavity is rare. Since 1980, nine cases have been reported. A 41-year-old patient showed a MCL presenting with a symmetric, painless palatal swelling without any other clinical symptoms. Histological sections revealed malignant monotonous lymphoid cells (CD20+, CD43+, Ki67+) and the typical cyclinD1 over-expression by the chromosomal translocation t(11;14)(q13;q32). The proliferating cells weekly expressed CD5, kappa-and lambda-light chains and no EMA, CD10, bcl-6, CD30, and CD23. The patient was treated according to the European MCL younger study, and the MCL is regressive. The high incidence of dento-alveolar abscesses, inflammations, or benign tumor-formations leads to associate any maxillary or palatal swelling with this clinical condition. Considering the serious consequences of a missed therapy a histological examination of any untypical "swelling" is demanded.


[FULL TEXT] [PDF]*
Print this article  Email this article
    

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3933    
    Printed89    
    Emailed0    
    PDF Downloaded254    
    Comments [Add]    
    Cited by others 2    

Recommend this journal

 

Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
Online since 15th Aug, 2007