|Year : 2004 | Volume
| Issue : 2 | Page : 94-95
Juvenile pleomorphic adenoma
Vindhya Savithri, S Sudha, PM Shameena, Varughese V Ipe
Department of Oral and Maxillofacial Pathology, Government Dental College, Calicut, India
Department Of Oral Pathology, Government Dental College, Calicut -673008
Source of Support: None, Conflict of Interest: None
| Abstract|| |
Pleomorphic aderoma is a benign mixed salivary gland tumour seen most commonly in the parotid gland and is usually found in 4th and 6th decade of life. This is a case report of an unusual occurrence in a child in a rare intro-oral site, It was clinically diagnosed as fibronia and later histopathological examination revealed it to be a pleomorphic adenoma.
|How to cite this article:|
Savithri V, Sudha S, Shameena P M, Ipe VV. Juvenile pleomorphic adenoma. J Oral Maxillofac Pathol 2004;8:94-5
| Introduction|| |
The terminology mixed salivary gland tumor. was first introduced in 1874 by Minssen  while the term pleomorphic adenoma was suggested by Willis  it is by far the most commonly occurring salivary gland tumour and the incidence in the parotid gland is 63%, while in the minor salivary gland. it is 43%.  It is characterized by histomorphologic heterogeneity. i.e.. it is composed of glandular& stromal elements in differing proportions. The stroma may be mucoid, myxoid or chondroid. Most tumours occur between the 4 th to 6 th decades and there is a slight female predominance  .
| Case Report|| |
A male patient aged 13 years reported to Govt. Dental College. Calicut with the complaint of a growth in the tipper labial sulcus of three months duration [Figure 1]. During this time, the growth was seen to be slowly enlarging insize.
General examination of the patient was done and revealed no abnormal findings. the family history and medical history were non-contributory Infra orally the oral hygiene of the patient was good and a growth of approximately 1.5*1sq. cm in size was seen in the labial sulcus in relation to the upper left premolars region. The growth was non-tender and non-fluctuant. It had a smooth surface and was mobile. There were no associated carious teeth and palpable lymph nodes in the cervical region. Radiologic examination also revealed no findings and a provisional diagnosis of fibrurna was made
All routine laboratory investigations were done and revealed no abnormally. The mass was then enucleated by blunt dissection and it appeared to be encapsulated. The specimen was then sent for histopathologic examination- The tissue section revealed the presence of a fibrous capsule. Epidielium was seen proliferating in a duct-like pattern [Figure 2]. Proliferating epithelium was seen forming duct-like structures and some of these duct like structures contained eosinophilic coagulum [Figure 2] Abundant mucus cells were also seen. Myxoid areas were observed in stroma. These features lead to the diagnosis of pleomorphic adenoma.
| Discussion|| |
Pleomorphic adenoma may be derived from dutal and or myoepithelial elements. A remarkable microscopic diversity can exist from one tumor to the next. as well as in different areas of the same tumour. Minor salivary glands are the 2nd most common site for salivary gland neoplasm (9% to 23%). Intra orally the palate(60%) is the most common site os coccurence followed by the upper lip(20%) and buccal mucosa(10%).This case involved the labial sulcus, which is a very unusal site,On scanning the available literature, we found that no cases have been reported to occur in the labial sulcus.
Ribeiro et al  reported that epithelial neoplasms of salivary gland origin are relatively uncummon in children and adolescents and the mean age of occurence was 1 1.8 years. Kessler et al  and Ogata H et al  in different studies concluded that all the benign salivary neoplasms in children were pleomorphic adenoma. Hentandcz et al  reported an incidence of 1.4% for pleomorphic adenoma in children.
Jorge et al  reported a study on cases of juvenile infra oral pleomorpiuc adenoma of which 80% patients were female. 40% of the cases affected the palate amid another 40% occurred in the upper lip while 20% were seen in tongue. The pleomorphic adenoma youngsters seems to have similar biological characteristics to its counter pare seen in adults. But long-term follow-up is necessary to rule out a recurrence [Figure 3].
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[Figure 1], [Figure 2], [Figure 3]