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An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
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Year : 2004  |  Volume : 8  |  Issue : 2  |  Page : 70-72
Role of alkaline phosphatase in fibrogenesis or fibrolysis


Department of Periodontics, College of Dental Sciences, Davangere, India

Correspondence Address:
K L Vandana
Department of Periodontics, College of Dental Sciences, Davangere - 577 004
India
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Source of Support: None, Conflict of Interest: None


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The enzymes alkaline phosphatase is implicated with osteogenesis and fibrogenesis by various groups of investigators. With the conflicting observations about the presence and activity of ALP in relation to areas of mineralization and conditions characterized by fibrogenesis and fibrolysis, it is felt most desirable to investigate this enzyme in relation with collagen synthesis and collagen destruction. So that it might throw some light on the possible relationship of ALP with these pathological conditions. It was concluded that ALP as a marker determined by histochemistry is more dependable and validated as the source could be confirmed. Hence for assessment of fibrogenetic activity of ALP, histochemistry is compulsory


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Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
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