Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contact Us Login 
An Official Publication of the Indian Association of Oral and Maxillofacial Pathologists


 
ORIGINAL RESEARCH Table of Contents   
Year : 2003  |  Volume : 7  |  Issue : 2  |  Page : 44-45
Estimation of serum antioxidant enzymes superoxide dismutase and glutathione peroxidase in oral submucous fibrosis: A biochemical study


1 Department of Oral and Maxillo Facial Pathology and Microbiology, GDCH, Nagpur, India
2 Professor of Biochemistry, Government Medical College and Hospital, Mumbai, India

Correspondence Address:
V K Hazarey
Department of OMFPM, GDCH, Nagpur 63
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

The aim of the present study was to estimate the serum status of antioxidants, superoxide dismutase (SOD) and glutathione peroxidase (GPX) in oral submucous fibrosis (OSF) which is a precancerous condition common in Indian subcontinent. A total of sixty subjects were included in the study comprising of 30 cases of oral submucous fibrosis and 30 healthy controls. The haemolysate levels of antioxidant enzymes (SOD and GPX) were estimated using Ciba corning express plus autoanalyzer for spectrometry. In OSF, serum antioxidant enzyme levels were found to be decreased (mean SOD 86.6320.36 and mean GPX 1.500.30 U/ml) compared to the control group (mean SOD 127.118.14 and mean GPX 2.710.43 U/ml). The results suggest that low values of SOD and GPX may be associated with the development of carcinoma in oral submucous fibrosis.


[FULL TEXT] [PDF Not available]*
Print this article  Email this article
    

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed10110    
    Printed284    
    Emailed1    
    PDF Downloaded1    
    Comments [Add]    

Recommend this journal

 

Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow
Online since 15th Aug, 2007